High-throughput investigation of diverse junction elements in RNA tertiary folding. Lagging-strand replication shapes the mutational landscape of the genome. ![]() Sabarinathan, R., Mularoni, L., Deu-Pons, J., Gonzalez-Perez, A. Nucleotide excision repair is impaired by binding of transcription factors to DNA. The role of DNA shape in protein–DNA recognition. ![]() Intrinsic DNA shape accounts for affinity differences between Hox-cofactor binding sites. Experimental maps of DNA structure at nucleotide resolution distinguish intrinsic from protein-induced DNA deformations. DNA sequence-dependent deformability deduced from protein–DNA crystal complexes. How B-DNA dynamics decipher sequence-selective protein recognition. Eukaryotic mismatch repair in relation to DNA replication. Instability and decay of the primary structure of DNA. ![]() Somatic and germline mutation periodicity follow the orientation of the DNA minor groove around nucleosomes. Compact, universal DNA microarrays to comprehensively determine transcription-factor binding site specificities.
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